Decoding Cancer Evolution: Integrating Genetic and Non-Genetic Insights

Genetic and Epigenetic of Medullary Thyroid Cancer

Medullary thyroid carcinoma (MTC) is an infrequent calcitonin-producing neuroendocrine tumor that initiates from the parafollicular C cells of the thyroid gland. Several genetic and epigenetic alterations are collaterally responsible for medullary thyroid carcinogenesis. In this review article, we shed light on all the genetic and epigenetic hallmarks of MTC. From the genetic perspective, RET, ...

Genetic insights into breast cancer risk

Since the identification of BRCA1 and BRCA2 much has been learned about the role of mutations in these genes and how they relate to disease risk. The primary population that has been screened for mutations in these genes has been women who have a family history of early onset breast and or ovarian cancer. The tumour characteristics of women who harbour a BRCA1 mutation are similar to those iden...

Genetic accommodation and behavioural evolution: insights from genomic studies

New Insights on Genetic Features of Neu-Laxova Syndrome

ABSTRACTBackground: This study aimed to present a rare case of Neu-Laxova syndrome (NLS) and review the newly revealed genetic features of the disease in hopes to find a way for early interventions.Case report: Female newborn with NLS was born at 30 weeks of gestation to consanguineous parents. The last prenatal ultrasound imaging revealed severe intrauterine growth restriction and microcephaly...

GENETIC AND NON-GENETIC THEORIES ON THE ETIOLOGY OF POLYCYSTIC OVARY SYNDROME: A REVIEW